Vancomycin Therapy for Severe Clostridium difficile--Associated Diarrhea
نویسندگان
چکیده
منابع مشابه
Antimicrobial therapy of Clostridium difficile-associated diarrhea.
Clostridium difficile-associated diarrhea (CDAD) is the most common etiologically-defined cause of hospital-acquired diarrhea. Caused by the toxins of certain strains of C difficile, CDAD represents a growing concern, with epidemic outbreaks in some hospitals where very aggressive and difficult-to-treat strains have recently been found. Incidence of CDAD varies ordinarily between 1 to 10 in eve...
متن کاملClostridium difficile-associated diarrhea.
At our hospital, the number of cases of Clostridium difficile-associated diarrhoea increased from 29 in 1993 to 210 in 1995. The case notes of 110 patients with C difficile-associated diarrhoea during the first 6 months of 1995 were analysed retrospectively. The majority of the patients (106) had received antibiotics before the onset of diarrhoea; 46 had received three or more different antibio...
متن کاملClostridium difficile – Associated Diarrhea Outbreaks
Sir—We read with interest the article by Pépin et al. [1], which reports that use of quinolones is a major risk factor for illness during an outbreak of Clostridium difficile–associated diarrhea (CDAD). These results confirm previous observations that quinolones and other antibiotics, such as third-generation cephalosporins, macrolides, broad-spectrumb-lactams, and aminoglycosides, are importan...
متن کاملInterruption of recurrent Clostridium difficile-associated diarrhea episodes by serial therapy with vancomycin and rifaximin.
Eight women who each experienced 4-8 episodes of Clostridium difficile-associated diarrhea were given a 2-week course of rifaximin therapy when they were asymptomatic, immediately after completing their last course of vancomycin therapy. Seven of the 8 patients experienced no further diarrhea recurrence. The patient who had a recurrence responded to a second course of rifaximin therapy, but rif...
متن کاملClostridium difficile-associated diarrhea after antibiotic treatment for traveler's diarrhea.
Diarrhea commonly affects international travelers. Episodes are usually short-lasting, but in some patients, symptoms may persist. Clostridium difficile infection should be excluded in travelers with prolonged disease. We report what is, to our knowledge, the first reported study of patients with C. difficile-associated diarrhea after receipt of antibiotic treatment for traveler's diarrhea.
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ژورنال
عنوان ژورنال: Clinical Infectious Diseases
سال: 2007
ISSN: 1058-4838,1537-6591
DOI: 10.1086/523719